Independent Study

regarding effectiveness of metabolic balance®

Metabolism Program Reduces Weight while also Improving Health and Personal Quality of Life

The metabolic balance® independent study conducted by Hochrhein-Institute has been published in late December 2010 in the "Journal of Nutrition and Metabolism". The study shows that the metabolic balance®program is an extremely efficient program for weight loss, which also has a positive effect on the health-related quality of life.

The study was conducted in collaboration with the Department of Quality Management and Social Medicine of the Albert Ludwig University Medical Center Freiburg. The study results clearly show that overweight individuals in particular can effectively reduce their weight using metabolic balance® and this weight loss can also be sustained over the long term. The scientists were also surprised by a clear improvement in the blood test results of participants over the course of the study as well as statements by the program participants about the clear improvements in their personal and health-related quality of life.

A widely recognised measure of the long-term success of outpatient weight loss programs is that the baseline weight is reduced by at least 5% and that this loss is sustained over one year. With the metabolism program metabolic balance®, 62.5% of the participants cleared this hurdle. A total of 31.1% of the program participants lost more than twice this recommendation, that is, more than 10% of the baseline body weight. In an evaluation study of an outpatient weight loss program, 50% of the participants must have achieved a target of 5% weight loss and 20% of the participants should have lost at least 10% in weight. Both goals were reached and exceeded using metabolic balance®.

That these results are not the norm is revealed by the evaluation study ‘I’m losing weight – the evaluated concept of the German Nutrition Society (Deutsche Gesellschaft für Ernährung, DGE) on weight loss and the long-term switch to a wholesome diet’ published in 2008. In this study 26% of the participants reduced their weight by 5% or more over the course of the one-year program, while 5% of the participants lost and kept off 10% and more.

Clearly indicated: Positive Changes in the State of Health and Quality of Life

What is particularly remarkable in the results from the current study are the positive changes in blood test results associated with the weight loss. These are also reflected in the very positiveassessments by the participants about their perception of the clear improvements in their health-related quality of life.

At the start of the study, only 38% of the participants indicated that their quality of life is not restricted in any way (normal value in Germany: 75%). Many complained of noticeable or  serious impairments. After one year the quality of life had clearly improved: 68% of the participants were now satisfied with their quality of life.

At the start of the study, 27% of the clients complained of serious health problems. After one year, this proportion had fallen to 11.3% and was thus practically equal to the mean value in the German population (10%).

metabolic balance® and the Metabolic Syndrome

Another result of the study shows that the systematic change in diet in accordance with the metabolic balance® system clearly improves the symptoms of metabolic syndrome (excess weight, diabetes, hypertension and lipid metabolism disorders). Of the clients suffering from metabolic syndrome at the start of the program, after one year 76% no longer met the criteria for this diagnosis.

View the complete study here.

1 Meffert, Cornelia; Gerdes, Nikolaus: Program Adherence and Effectiveness of a Commercial Nutrition Program: The Metabolic Balance Study. Journal of Nutrition and Metabolism, Volume 2010 (2010), Article ID 197656;  (

2 P. R. Thomas, Ed., Committee to Develop Criteria for Evaluating the Outcomes of Approaches to Prevent and Treat Obesity and Institute of Medicine: Weighing the Options: Criteria for Evaluating Weight-Management Programs, National Academies Press, Washington, DC, USA, 1995

3 Hauner H, Wechsler JG, Kluthe R et al: Qualitätskriterien für ambulante Adipositasprogramme [Quality criteria for outpatient obesity programs],  Akt. Ernaehr. Med. 25 (2000), 163-165

metabolic balance® Evaluation Study

Improvement of parameters of the metabolic syndrome among study participants after 1 year.


Long-term weight reduction of ≥ 5% achieved by 62,5% of participants
Weight reduction of ≥10% achieved by 33% of participants

Improvement of health-related quality of life according to IRES-24

Do you have any questions?